conclusions a modified tool to assess methadone treatment response serves to identify patients at high-risk for relapse at a minimal cost, as well as evaluate the relevant physical and psycho-social domains affecting opioid-dependent patients. the great will serve as a useful adjunct to regular clinical assessments, allowing clinicians and researchers to properly assess opioid addiction patient...

buprenorphine (subutex) has been used to treat opioid dependency in the past 16 years. subutex (or buprenorphine hydrochloride) was approved by the singapore's ministry of health (moh) in 2000 as a substitution treatment for opiate-dependent drug abusers within the framework of medical, social and psychological treatments. it was subsequently introduced into the singapore market in 2002. i...

recent studies on rodents showed successful treatment outcomes for cocaine dependence by using buprenorphine and naltrexone without the risk of dependence on them. such findings could provide a new hope on treatment of cocaine, methamphetamine or other stimulants dependence. the idea of using these medicines was formed once dr. nora volkow (director of nation institute for drug abuse) based on ...

methadone is widely being used for opioid substitution therapy. however, the administration of methadone to opioid dependent individual is frequently accompanied by withdrawal syndrome and chemical dependency develops. other than that, it is also difficult to retain patients in the treatment programme making their retention rates are decreasing over time. this article is written to higlights th...

background : the existing evidence about the clinical situations of the bipolar patients with opioid dependence is scarce. the present study was carried out to compare the clinical features and course of the bipolar disorder type i regarding the two subgroups of opioid dependent and non-dependent. methods : there were 178 adult patients with bipolar disorder type i consecutively referred to the...

This publication presents an overview of the practices and the context of pharmacotherapy of opioid dependence in selected countries of the South East Asia and Western Pacific regions of the World Health Organisation. Based on reports provided by professionals involved in treatment of opioid dependence in these regions, the document describes the current situation with opioid use and its health...

BACKGROUND Addiction to opioids, or opioid dependence, encompasses the biopsychosocial dysfunction seen in illicit heroin injectors, as well as aberrant behaviours in patients prescribed opioids for chronic nonmalignant pain. OBJECTIVE To outline the management of opioid dependence using opioid pharmacotherapy as part of a comprehensive chronic illness management strategy. DISCUSSION The sa...